Drug Detail


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Drug Name LBL-007
Trade Name
Synonyms LBL007|LBL 007
Drug Descriptions

LBL-007 targets LAG3 and prevents its interaction with MHC II molecules and liver sinusoidal endothelial cell lectin, potentially leading to relief of LAG-3 mediated immunosuppression and decreased tumor growth (PMID: 31242068).

DrugClasses LAG3 Antibody 18
CAS Registry Number NA
NCIT ID C179260


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Capecitabine + LBL-007 Bevacizumab Capecitabine LBL-007 0 1
Bevacizumab + Capecitabine + LBL-007 + Tislelizumab Bevacizumab Capecitabine LBL-007 Tislelizumab 0 1
Bevacizumab + Fluorouracil + LBL-007 Bevacizumab Fluorouracil LBL-007 0 1
Bevacizumab + Fluorouracil + LBL-007 + Tislelizumab Bevacizumab Fluorouracil LBL-007 Tislelizumab 0 1
BGB-A425 + LBL-007 + Tislelizumab BGB-A425 LBL-007 Tislelizumab 0 1
Carboplatin + LBL-007 + Tislelizumab Carboplatin LBL-007 Tislelizumab 0 0
Cisplatin + LBL-007 + Tislelizumab Cisplatin LBL-007 Tislelizumab 0 0
LBL-007 LBL-007 0 0
LBL-007 + Paclitaxel + Tislelizumab LBL-007 Paclitaxel Tislelizumab 0 0
LBL-007 + Tislelizumab LBL-007 Tislelizumab 0 2
LBL-007 + Toripalimab-tpzi LBL-007 Toripalimab-tpzi 0 0
LBL-007 + unspecified PD-1 antibody LBL-007 unspecified PD-1 antibody 0 0

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