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Drug Name SHR-1701
Trade Name
Synonyms SHR 1701|SHR1701
Drug Descriptions

SHR-1701 is a monoclonal anti-PD-L1 antibody fused to the extracellular domain of Tgfbr2, which may trap TGFbeta and block TGFbeta-mediated immune suppression, leading to enhanced response to PD-L1 inhibition (J Clin Oncol 39, no. 15_suppl (May 20, 2021) 9055-9055).

DrugClasses Immune Checkpoint Inhibitor 149 PD-L1 Inhibitor 11 TGFB inhibitor 5
CAS Registry Number
NCIT ID C178398

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Famitinib + SHR-1701 Famitinib SHR-1701 0 0
SHR-1701 SHR-1701 0 1


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