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Drug Name OH2
Trade Name
Synonyms OH-2|OH 2|oHSV-2-expressing GM-CSF OH2
Drug Descriptions

OH2 is an oncolytic herpes simplex virus-2 (HSV-2) engineered to include deletions in the viral genes ICP34.5 and ICP47, and to express human granulocyte macrophage colony stimulating factor (GM-CSF), which may lead to the activation of anti-tumor immune response and tumor cell killing (PMID: 32055679, PMID: 29872496).

DrugClasses
CAS Registry Number NA
NCIT ID C172106

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Therapy Name Drugs Efficacy Evidence Clinical Trials
HX008 + OH2 HX008 OH2 0 0
OH2 OH2 0 0


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