Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name H3K27M peptide vaccine
Trade Name
Synonyms H3K27M long peptide vaccine
Drug Descriptions

H3K27M peptide vaccine is comprised of a 27mer immunogenic peptide derived from histone H3 harboring the K27M mutation (also referred to as K28M), which may lead to activation of immune response against tumor cells expressing H3K27M and tumor growth inhibition (PMID: 28811969).

CAS Registry Number NA
NCIT ID C180377


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + H3K27M peptide vaccine + Imiquimod Atezolizumab H3K27M peptide vaccine Imiquimod 0 1
H3K27M peptide vaccine H3K27M peptide vaccine 0 0

Additional content available in CKB BOOST