Drug Detail


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Drug Name ACT001
Trade Name
Synonyms ACT-001|ACT 001
Drug Descriptions

ACT001 binds to SERPINE1 (PAI-1) and inhibits PI3K/AKT pathway signaling, potentially leading to inhibition of tumor cell proliferation and migration and decreased tumor growth (PMID: 31591377).

CAS Registry Number NA
NCIT ID C182143


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ACT001 ACT001 0 1
ACT001 + Cisplatin ACT001 Cisplatin 0 0
ACT001 + Pembrolizumab ACT001 Pembrolizumab 0 1

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