Drug Detail


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Drug Name XTX101
Trade Name
Synonyms XTX 101|XTX-101
Drug Descriptions

XTX101 is an anti-CTLA4 antibody engineered for tumor microenvironment-specific activity, which may lead to proliferation of CD8+ T lymphocytes, activation of T lymphocyte function, and tumor regression (Journal for ImmunoTherapy of Cancer 2020;8)

DrugClasses CTLA4 Antibody 21
CAS Registry Number NA
NCIT ID C180687


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + XTX101 Pembrolizumab XTX101 0 1
XTX101 XTX101 0 1

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