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Drug Name CEND-1
Trade Name
Synonyms CEND1|CEND 1|LSTA 1|LSTA-1|LSTA1|iRGD
Drug Descriptions

CEND-1 is a peptide that is targeted to tumors via interaction with alpha-integrins and potentially increases the delivery of other antitumor agents via interaction with neuropilin-1 (Annals of Oncology 31 (2020): S941).

DrugClasses
CAS Registry Number 1392278-76-0
NCIT ID C103858

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Therapy Name Drugs Efficacy Evidence Clinical Trials
CEND-1 CEND-1 0 1
CEND-1 + Cisplatin + Durvalumab + Gemcitabine CEND-1 Cisplatin Durvalumab Gemcitabine 0 1
CEND-1 + Docetaxel CEND-1 Docetaxel 0 1
CEND-1 + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin CEND-1 Fluorouracil Irinotecan Leucovorin Oxaliplatin 0 1
CEND-1 + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Panitumumab CEND-1 Fluorouracil Irinotecan Leucovorin Oxaliplatin Panitumumab 0 1
CEND-1 + Gemcitabine + Nab-paclitaxel CEND-1 Gemcitabine Nab-paclitaxel 0 1
CEND-1 + Paclitaxel CEND-1 Paclitaxel 0 1


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