Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name BGB-11417
Trade Name
Synonyms BGB 11417|BGB11417
Drug Descriptions

BGB-11417 selectively inhibits Bcl2, which potentially leads to decreased tumor cell proliferation and inhibition of tumor growth (Cancer Res 2020;80(16 Suppl):Abstract nr 3077).

DrugClasses BCL2 inhibitor 24
CAS Registry Number NA
NCIT ID C175489

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + BGB-11417 Azacitidine BGB-11417 0 1
Azacitidine + BGB-11417 + Posaconazole Azacitidine BGB-11417 Posaconazole 0 0
BGB-11417 BGB-11417 0 1
BGB-11417 + Carfilzomib + Dexamethasone BGB-11417 Carfilzomib Dexamethasone 0 1
BGB-11417 + Dexamethasone BGB-11417 Dexamethasone 0 1
BGB-11417 + Zanubrutinib BGB-11417 Zanubrutinib 0 1


Additional content available in CKB BOOST