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Drug Name ASP2453
Trade Name
Synonyms
Drug Descriptions

ASP2453 is a selective inhibitor of KRAS G12C, which blocks downstream signaling and potentially inhibits growth of tumor cells harboring KRAS G12C (PMID: 34795410).

DrugClasses KRAS G12C inhibitor 18
CAS Registry Number 2241719-73-1
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ASP2453 ASP2453 0 0
ASP2453 + Erlotinib ASP2453 Erlotinib 0 0
ASP2453 + Trametinib ASP2453 Trametinib 0 0
ASP2453 + unspecified PD-1 antibody ASP2453 unspecified PD-1 antibody 0 0


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