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Drug Name MVC-101
Trade Name
Synonyms MVC 101|MVC101|TAK 186|TAK-186|TAK186
Drug Descriptions

MVC-101 is a bispecific T cell engager that targets EGFR expressed on tumor cells and CD3 antigen found on T cells, which upon proteolytic cleavage of the linker potentially leads to T cell activation against tumor cells and subsequent tumor regression (PMID: 32684124).

DrugClasses CD3 Antibody 56 EGFR Antibody 39
CAS Registry Number NA
NCIT ID C180595

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Therapy Name Drugs Efficacy Evidence Clinical Trials
MVC-101 MVC-101 0 1
MVC-101 + Nivolumab MVC-101 Nivolumab 0 1


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