Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Setanaxib
Trade Name
Synonyms GKT137831
Drug Descriptions

Setanaxib (GKT137831) inhibits NADPH oxidase isoform 1 (NOX1) and isoform 4 (NOX4) (PMID: 20942471), and may potentially alter reactive oxygen species levels and decrease tumor cell growth (PMID: 35326163).

CAS Registry Number 1218942-37-0
NCIT ID C166721


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + Setanaxib Pembrolizumab Setanaxib 0 1
Setanaxib Setanaxib 0 0

Additional content available in CKB BOOST