Drug Detail


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Drug Name AMX-818
Trade Name
Synonyms AMX 818|AMX818
Drug Descriptions

AMX-818 is a prodrug T-cell engager that targets CD3 and ERBB2 (HER2) which is activated in the tumor microenvironment, potentially resulting in activation of an immune response against ERBB2 (HER2)-expressing tumors and inhibition of tumor growth (Mol Cancer Ther 2021;20(12 Suppl):Abstract nr P193).

DrugClasses CD3 Antibody 56 HER2 (ERBB2) Antibody 57
CAS Registry Number NA


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AMX-818 AMX-818 0 1
AMX-818 + Pembrolizumab AMX-818 Pembrolizumab 0 1

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