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Drug Name NTX-1088
Trade Name
Synonyms NTX 1088|NTX1088
Drug Descriptions

NTX-1088 is a monoclonal antibody that targets the poliovirus receptor (PVR, CD155), thereby preventing its interaction with CD96 and TIGIT as well as DNAM1 (CD226), potentially leading to enhanced antitumor immune response and inhibition of tumor growth (Cancer Immunol Res 2022;10(1 Suppl):Abstract nr P075).

DrugClasses
CAS Registry Number NA
NCIT ID C188066

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Therapy Name Drugs Efficacy Evidence Clinical Trials
NTX-1088 NTX-1088 0 1
NTX-1088 + Pembrolizumab NTX-1088 Pembrolizumab 0 1


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