Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name SOT102
Trade Name
Synonyms SOT-102|SOT 102|SO N102|SO-N102|SON102
Drug Descriptions

SOT102 is an antibody-drug conjugate (ADC) comprising a claudin 18.2 (CLDN18.2)-targeted antibody linked to a derivative of the cytotoxic anthracycline PNU-159682, which potentially leads to impaired DNA replication and protein synthesis, resulting in killing of tumor cells expressing CLDN18.2 (NCI Drug Dictionary).

DrugClasses CLDN18.2 Antibody 18
CAS Registry Number NA
NCIT ID C190788

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Fluorouracil + Leucovorin + Nivolumab + Oxaliplatin + SOT102 Fluorouracil Leucovorin Nivolumab Oxaliplatin SOT102 0 1
Gemcitabine + Nab-paclitaxel + SOT102 Gemcitabine Nab-paclitaxel SOT102 0 1
SOT102 SOT102 0 1


Additional content available in CKB BOOST