Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Dapansutrile
Trade Name
Synonyms OLT1177|OLT 1177|OLT-1177
Drug Descriptions

Dapansutrile inhibits NLRP3 by blocking ATPase activity, which potentially reduces myeloid-derived suppressor cell expansion and tumor growth (PMID: 33649199).

DrugClasses
CAS Registry Number 54863-37-5
NCIT ID C166608

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Dapansutrile Dapansutrile 0 0
Dapansutrile + Pembrolizumab Dapansutrile Pembrolizumab 0 1
Dapansutrile + unspecified PD-L1 antibody Dapansutrile unspecified PD-L1 antibody 0 0


Additional content available in CKB BOOST