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Drug Name ELVN-002
Trade Name
Synonyms ELVN002|ELVN 002
Drug Descriptions

ELVN-002 selectively inhibits ERBB2 (HER2), including mutant ERBB2 (HER2), potentially leading to decreased tumor cell proliferation and reduced growth of ERBB2 (HER2)-expressing and ERBB2 (HER2)-mutant tumors (Cancer Res (2023) 83 (7_Supplement): 4019).
DrugClasses HER2 Inhibitor 41
CAS Registry Number NA
NCIT ID C192219

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Ado-trastuzumab emtansine + ELVN-002 Ado-trastuzumab emtansine ELVN-002 0 1
Capecitabine + ELVN-002 + Oxaliplatin + Trastuzumab Capecitabine ELVN-002 Oxaliplatin Trastuzumab 0 1
Capecitabine + ELVN-002 + Trastuzumab Capecitabine ELVN-002 Trastuzumab 0 1
ELVN-002 ELVN-002 0 1
ELVN-002 + Eribulin + Trastuzumab ELVN-002 Eribulin Trastuzumab 0 1
ELVN-002 + Fluorouracil + Leucovorin + Oxaliplatin + Trastuzumab ELVN-002 Fluorouracil Leucovorin Oxaliplatin Trastuzumab 0 1
ELVN-002 + Paclitaxel + Trastuzumab ELVN-002 Paclitaxel Trastuzumab 0 1
ELVN-002 + Trastuzumab ELVN-002 Trastuzumab 0 1
ELVN-002 + Trastuzumab deruxtecan ELVN-002 Trastuzumab deruxtecan 0 1


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