Drug Detail


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Drug Name MTX-1000
Trade Name
Synonyms MTX1000|MTX 1000
Drug Descriptions

MTX-1000 is an antibody-drug conjugate (ADC) comprising an ERBB2 (HER2) antibody linked to exatecan, which upon internalization may result in tumor cell killing and decreased growth of ERBB2 (HER2)-expressing tumors (PMID: 36693125).

DrugClasses HER2 (ERBB2) Antibody-Drug Conjugate 24
CAS Registry Number NA


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Therapy Name Drugs Efficacy Evidence Clinical Trials
MTX-1000 MTX-1000 0 0
MTX-1000 + Talazoparib MTX-1000 Talazoparib 0 0
MTX-1000 + VX-803 MTX-1000 VX-803 0 0

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