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Drug Name Cladribine
Trade Name Leustatin
Synonyms 2-CdA
Drug Descriptions

Leustatin (cladribine) is a purine analog that is incorporated into DNA, resulting in DNA single strand breaks and apoptosis (NCI Drug Dictionary).

DrugClasses
CAS Registry Number 4291-63-8
NCIT ID C1336

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + Cladribine + Cytarabine + Venetoclax Azacitidine Cladribine Cytarabine Venetoclax 0 1
Bortezomib + Cladribine + Rituximab Bortezomib Cladribine Rituximab 0 1
Busulfan + Cladribine + Fludarabine + Thiotepa + Venetoclax Busulfan Cladribine Fludarabine Thiotepa Venetoclax 0 1
Cladribine Cladribine 0 7
Cladribine + Cytarabine + Filgrastim Cladribine Cytarabine Filgrastim 0 2
Cladribine + Cytarabine + Filgrastim + Gemtuzumab ozogamicin Cladribine Cytarabine Filgrastim Gemtuzumab ozogamicin 0 1
Cladribine + Cytarabine + Filgrastim + Gemtuzumab ozogamicin + Mitoxantrone Cladribine Cytarabine Filgrastim Gemtuzumab ozogamicin Mitoxantrone 0 1
Cladribine + Cytarabine + Filgrastim + Gilteritinib + Mitoxantrone Cladribine Cytarabine Filgrastim Gilteritinib Mitoxantrone 0 1
Cladribine + Cytarabine + Filgrastim + Idarubicin Cladribine Cytarabine Filgrastim Idarubicin 0 1
Cladribine + Cytarabine + Filgrastim + Mitoxantrone Cladribine Cytarabine Filgrastim Mitoxantrone 0 3
Cladribine + Cytarabine + Filgrastim + Mitoxantrone + Navitoclax + Venetoclax Cladribine Cytarabine Filgrastim Mitoxantrone Navitoclax Venetoclax 0 1
Cladribine + Cytarabine + Idarubicin Cladribine Cytarabine Idarubicin 0 1
Cladribine + Cytarabine + Idarubicin + Quizartinib Cladribine Cytarabine Idarubicin Quizartinib 0 1
Cladribine + Cytarabine + Mitoxantrone + Sargramostim + Venetoclax Cladribine Cytarabine Mitoxantrone Sargramostim Venetoclax 0 1
Cladribine + Cytarabine + Navitoclax + Venetoclax Cladribine Cytarabine Navitoclax Venetoclax 0 1
Cladribine + Cytarabine + Plerixafor Cladribine Cytarabine Plerixafor 0 1
Cladribine + Cytarabine + Uproleselan Cladribine Cytarabine Uproleselan 0 1
Cladribine + Cytarabine + Venetoclax Cladribine Cytarabine Venetoclax 0 1
Cladribine + Rituximab Cladribine Rituximab 0 2


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