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Drug Name Epirubicin
Trade Name Ellence
Synonyms Epirubicin Hydrochloride
Drug Descriptions

Ellence (epirubicin) is an anthracycline, which intercalates into DNA and inhibits topoisomerase II (PMID: 24367159). Ellence (epirubicin) is FDA approved as a component of adjuvant therapy in patients with evidence of axillary node tumor involvement for primary breast cancer (FDA.gov).

DrugClasses Chemotherapy - Anthracycline 11

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AKI603 + Epirubicin AKI603 Epirubicin 1 0
Atezolizumab + Cyclophosphamide + Epirubicin + Paclitaxel Atezolizumab Cyclophosphamide Epirubicin Paclitaxel 0 1
Bevacizumab + Cyclophosphamide + Docetaxel + Epirubicin + Fluorouracil Bevacizumab Cyclophosphamide Docetaxel Epirubicin Fluorouracil 1 0
Capecitabine + Cisplatin + Epirubicin + Gemcitabine Capecitabine Cisplatin Epirubicin Gemcitabine 0 0
Capecitabine + Cisplatin + Epirubicin + Gemcitabine + Metformin Capecitabine Cisplatin Epirubicin Gemcitabine Metformin 1 0
Capecitabine + Cisplatin + Epirubicin + Rilotumumab Capecitabine Cisplatin Epirubicin Rilotumumab 0 0
Capecitabine + Epirubicin + Oxaliplatin + Pembrolizumab Capecitabine Epirubicin Oxaliplatin Pembrolizumab 0 1
Cetuximab + Cisplatin + Epirubicin + Fluorouracil Cetuximab Cisplatin Epirubicin Fluorouracil 1 0
Cyclophosphamide + Docetaxel + Epirubicin + Fluorouracil Cyclophosphamide Docetaxel Epirubicin Fluorouracil 0 1
Cyclophosphamide + EG12014 + Epirubicin + Paclitaxel Cyclophosphamide EG12014 Epirubicin Paclitaxel 0 1
Cyclophosphamide + Epirubicin Cyclophosphamide Epirubicin 0 3
Cyclophosphamide + Epirubicin + Fluorouracil Cyclophosphamide Epirubicin Fluorouracil 0 3
Cyclophosphamide + Epirubicin + Fluorouracil + Pertuzumab + Trastuzumab Cyclophosphamide Epirubicin Fluorouracil Pertuzumab Trastuzumab 0 1
Cyclophosphamide + Epirubicin + Paclitaxel Cyclophosphamide Epirubicin Paclitaxel 0 2
Cyclophosphamide + Epirubicin + Paclitaxel + Pembrolizumab Cyclophosphamide Epirubicin Paclitaxel Pembrolizumab 0 1
Cyclophosphamide + Epirubicin + Paclitaxel + Trastuzumab Cyclophosphamide Epirubicin Paclitaxel Trastuzumab 0 1
Cyclophosphamide + Epirubicin + Pembrolizumab Cyclophosphamide Epirubicin Pembrolizumab 0 0
Docetaxel + Epirubicin Docetaxel Epirubicin 0 1
Epirubicin Epirubicin 0 1
Epirubicin + Ifosfamide + Sorafenib Epirubicin Ifosfamide Sorafenib 0 1
Epirubicin + Panobinostat Epirubicin Panobinostat 1 0
Epirubicin + Pembrolizumab Epirubicin Pembrolizumab 0 0
Epirubicin + Valproic acid Epirubicin Valproic acid 1 0


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