Drug Detail


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Drug Name Gonadorelin
Trade Name
Synonyms Dirigestran|GnRH|LHRHA|AY-24031
Drug Descriptions

Gonadorelin is a synthetic version of gonatotropin-releasing hormone (GnRH) that binds GnRH receptors and induces gonatotropic hormone release, and leads to down-regulation of GnRH receptor expression and reduced hormone release following sustained exposure (NCI Drug Dictionary).

DrugClasses Hormone Antineoplastics 5
CAS Registry Number 33515-09-2


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Apalutamide + Gonadorelin + Prednisone Abiraterone Apalutamide Gonadorelin Prednisone 0 1
Apalutamide + Gonadorelin + Radiotherapy Apalutamide Gonadorelin Radiotherapy 0 1
Bicalutamide + Gonadorelin Bicalutamide Gonadorelin 0 1
Gonadorelin Gonadorelin 0 0
Gonadorelin + Radiotherapy Gonadorelin Radiotherapy 0 1

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