Drug Detail


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Drug Name Amuvatinib
Trade Name
Synonyms MP470|HPK56|MP-470
Drug Descriptions

Amuvatinib (MP470) is a multi-kinase inhibitor, with activity against KIT, MET, AXL, RET, FLT3, and PDGFR-alpha, that also inhibits Rad51 induction, which may enhance the efficacy of chemotherapeutic agents (PMID: 17325667, PMID: 21903282, PMID: 20563581, PMID: 24849582).

DrugClasses AXL Inhibitor 30 FLT3 Inhibitor 68 KIT Inhibitor 57 MET Inhibitor 59 PDGFR-alpha Inhibitor 9 RET Inhibitor 52
CAS Registry Number 850879-09-3
NCIT ID C71750


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Amuvatinib Amuvatinib 0 0
Amuvatinib + Carboplatin + Paclitaxel Amuvatinib Carboplatin Paclitaxel 0 0

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