Drug Detail


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Drug Name Onatasertib
Trade Name
Synonyms CC-223|ATG-008
Drug Descriptions

Onatasertib (CC-223) is a selective inhibitor of mTOR that induces apoptosis and growth inhibition in tumor cells (PMID: 25855786, PMID: 31527867).

DrugClasses mTOR Inhibitor 51
CAS Registry Number 1228013-30-6
NCIT ID C92575


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ATG-012 + Onatasertib ATG-012 Onatasertib 0 0
Azacitidine + Onatasertib Azacitidine Onatasertib 0 1
CC-122 + Onatasertib CC-122 Onatasertib 0 1
Erlotinib + Onatasertib Erlotinib Onatasertib 0 1
Onatasertib Onatasertib 2 1
Onatasertib + Spebrutinib Onatasertib Spebrutinib 0 1
Onatasertib + Toripalimab-tpzi Onatasertib Toripalimab-tpzi 0 0

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