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Drug Name Ganetespib
Trade Name
Synonyms STA-9090
Drug Descriptions

Ganetespib is a small molecule that inhibits Hsp90, resulting in the degradation and inactivation of Hsp90 client proteins and decreased cell proliferation (PMID: 26244021).

DrugClasses HSP90 Inhibitor 35
CAS Registry Number 1143571-94-1
NCIT ID C77872

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + Ganetespib Afatinib Ganetespib 0 0
Aflibercept + Ganetespib Aflibercept Ganetespib 0 1
Aldoxorubicin + Ganetespib Aldoxorubicin Ganetespib 0 1
Carboplatin + Ganetespib + Paclitaxel + Radiotherapy Carboplatin Ganetespib Paclitaxel Radiotherapy 0 0
Carboplatin + Ganetespib + Pemetrexed Disodium Carboplatin Ganetespib Pemetrexed Disodium 0 0
Cisplatin + Ganetespib + Pemetrexed Disodium Cisplatin Ganetespib Pemetrexed Disodium 0 0
Crizotinib + Ganetespib Crizotinib Ganetespib 0 1
Erlotinib + Ganetespib Erlotinib Ganetespib 0 0
Ganetespib Ganetespib 7 7
Ganetespib + Infigratinib Ganetespib Infigratinib 0 0
Ganetespib + Paclitaxel + Trastuzumab Ganetespib Paclitaxel Trastuzumab 0 1
Ganetespib + Radiotherapy Ganetespib Radiotherapy 0 0
Ganetespib + Sirolimus Ganetespib Sirolimus 0 1
Ganetespib + TAK-733 Ganetespib TAK-733 1 0


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