Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Ganetespib
Trade Name
Synonyms STA-9090
Drug Descriptions

Ganetespib is a small molecule that inhibits Hsp90, resulting in the degradation and inactivation of Hsp90 client proteins and decreased cell proliferation (PMID: 26244021).

DrugClasses HSP90 Inhibitor 35

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + Ganetespib Afatinib Ganetespib 0 0
Aflibercept + Ganetespib Aflibercept Ganetespib 0 1
Aldoxorubicin + Ganetespib Aldoxorubicin Ganetespib 0 1
Carboplatin + Ganetespib + Paclitaxel + Radiotherapy Carboplatin Ganetespib Paclitaxel Radiotherapy 1 0
Crizotinib + Ganetespib Crizotinib Ganetespib 0 1
Erlotinib + Ganetespib Erlotinib Ganetespib 0 0
Ganetespib Ganetespib 9 7
Ganetespib + Infigratinib Ganetespib Infigratinib 1 0
Ganetespib + Paclitaxel + Trastuzumab Ganetespib Paclitaxel Trastuzumab 0 1
Ganetespib + Radiotherapy Ganetespib Radiotherapy 1 0
Ganetespib + Sirolimus Ganetespib Sirolimus 2 1
Ganetespib + TAK-733 Ganetespib TAK-733 1 0


Additional content available in CKB BOOST