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Drug Name Pictilisib
Trade Name
Synonyms GDC-0941
Drug Descriptions

Pictilisib (GDC-0941) inhibits isoforms of PI3K, which inhibits PI3K/AKT signaling resulting in antitumor activity, including inhibition of tumor growth (PMID: 19584227).

DrugClasses PI3K Inhibitor (Pan) 37

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Anastrozole + Pictilisib Anastrozole Pictilisib 0 0
ARS1620 + Pictilisib ARS1620 Pictilisib 0 0
Binimetinib + Pictilisib Binimetinib Pictilisib 0 0
Cisplatin + Pictilisib Cisplatin Pictilisib 2 1
Cobimetinib + Pictilisib Cobimetinib Pictilisib 0 1
Encorafenib + Pictilisib Encorafenib Pictilisib 0 0
Erlotinib + Pictilisib Erlotinib Pictilisib 1 0
Everolimus + Pictilisib + Trametinib Everolimus Pictilisib Trametinib 0 0
Fulvestrant + Palbociclib + Pictilisib Fulvestrant Palbociclib Pictilisib 0 0
Fulvestrant + Pictilisib Fulvestrant Pictilisib 1 0
GDC0879 + Pictilisib GDC0879 Pictilisib 0 0
Gefitinib + Pictilisib Gefitinib Pictilisib 0 0
Gemcitabine + Pictilisib Gemcitabine Pictilisib 2 0
Infigratinib + Pictilisib Infigratinib Pictilisib 0 0
Lapatinib + Pictilisib Lapatinib Pictilisib 1 0
Linsitinib + Pictilisib Linsitinib Pictilisib 1 0
MRTX849 + Pictilisib MRTX849 Pictilisib 0 0
MS417 + Pictilisib MS417 Pictilisib 1 0
Navitoclax + Pictilisib Navitoclax Pictilisib 2 0
Neratinib + Pictilisib Neratinib Pictilisib 1 0
NVP-AEW541 + Pictilisib NVP-AEW541 Pictilisib 1 0
Palbociclib + Pictilisib Palbociclib Pictilisib 3 0
PD-0325901 + Pictilisib PD-0325901 Pictilisib 1 0
Pictilisib Pictilisib 11 2
Pictilisib + PLX4720 PLX4720 Pictilisib 0 0
Pictilisib + Ruxolitinib Pictilisib Ruxolitinib 5 0
Pictilisib + SCH772984 Pictilisib SCH772984 0 0
Pictilisib + Selumetinib Pictilisib Selumetinib 0 0
Pictilisib + Sorafenib Pictilisib Sorafenib 1 0
Pictilisib + Venetoclax Pictilisib Venetoclax 0 0
Pictilisib + Vorinostat Pictilisib Vorinostat 0 0


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