Drug Detail


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Drug Name KX2-391
Trade Name
Synonyms KX-01|Tirbanibulin
Drug Descriptions

Tirbanibulin (KX2-391) is a peptidomimetic inhibitor of Src and pretubulin, with additional activity against FLT3, potentially resulting in decreased tumor growth and metastasis (PMID: 22784709, PMID: 31628188, PMID: 34217323).

DrugClasses FLT3 Inhibitor 69 SRC Inhibitor 31
CAS Registry Number 897016-82-9
NCIT ID C74077


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Therapy Name Drugs Efficacy Evidence Clinical Trials
KX2-391 KX2-391 11 2
KX2-391 + Oxaliplatin KX2-391 Oxaliplatin 2 0
KX2-391 + Paclitaxel KX2-391 Paclitaxel 1 0
KX2-391 + Tamoxifen KX2-391 Tamoxifen 0 0

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