Drug Detail


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Drug Name TAK-733
Trade Name
Synonyms TAK733
Drug Descriptions

TAK-733 inhibits MEK1 and MEK2, preventing the activation of the RAS/RAF/MEK/ERK pathway, possibly inhibiting growth factor-mediated cell signaling and tumor cell proliferation (PMID: 26439693, PMID: 30396931).

DrugClasses MEK inhibitor (Pan) 23 MEK1 Inhibitor 22 MEK2 Inhibitor 20
CAS Registry Number 1035555-63-5
NCIT ID C84858


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Ganetespib + TAK-733 Ganetespib TAK-733 1 0
TAK-733 TAK-733 3 0

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