Drug Detail


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Drug Name Volasertib
Trade Name
Synonyms BI 6727|BI6727|BI-6727
Drug Descriptions

Volasertib (BI 6727) inhibits polo-like kinase I (PLK1), resulting in cell cycle arrest and apoptosis in tumor cells (PMID: 27330107, PMID: 30782614, PMID: 32728610).

DrugClasses PLK1 Inhibitor 18
CAS Registry Number 755038-65-4
NCIT ID C79844


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Belinostat + Volasertib Belinostat Volasertib 0 1
Cytarabine + Idarubicin + Volasertib Cytarabine Idarubicin Volasertib 0 2
Cytarabine + Volasertib Cytarabine Volasertib 0 0
Decitabine + Volasertib Decitabine Volasertib 0 1
Eribulin + Volasertib Eribulin Volasertib 0 0
Fulvestrant + Palbociclib + Volasertib Fulvestrant Palbociclib Volasertib 0 0
Paclitaxel + Volasertib Paclitaxel Volasertib 0 0
RXDX-105 + Volasertib RXDX-105 Volasertib 0 0
Trametinib + Volasertib Trametinib Volasertib 0 0
Vincristine Sulfate + Volasertib Vincristine Sulfate Volasertib 0 1
Volasertib Volasertib 1 1

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