Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Drug Name | XL999 |
Trade Name | |
Synonyms | XL-999|XL 999 |
Drug Descriptions |
XL999 inhibits multiple tyrosine kinases including VEGFR2/KDR, FGFR1/3, PDGFR-beta, FLT3, RET, KIT, and SRC, which can result in anti-tumor activity (J Clin Oncol, 25:18s, 2007 (suppl;abstr 3591), PMID: 19581523). |
DrugClasses | FGFR1 Inhibitor 28 FGFR3 Inhibitor 19 FLT3 Inhibitor 65 KIT Inhibitor 57 PDGFR-beta Inhibitor 14 RET Inhibitor 52 SRC Inhibitor 31 VEGFR2 Inhibitor 37 |
CAS Registry Number | 921206-68-0 |
NCIT ID | C116894 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
XL999 | XL999 | 0 | 0 |