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Drug Name SNX-5422
Trade Name
Synonyms PF-04929113|PF 04929113|SNX 5422
Drug Descriptions

SNX-5422 (PF-04929113) is the prodrug of the potent Hsp90 inhibitor SNX-2112, which has been shown to decrease activation Her-2, Akt, and ERK, inhibit tumor cell proliferation, and induce tumor cell apoptosis (PMID: 21349995, PMID: 18948577, PMID: 32468060).

DrugClasses HSP90 Inhibitor 35
CAS Registry Number 908115-27-5
NCIT ID C141504


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Paclitaxel + SNX-5422 Carboplatin Paclitaxel SNX-5422 0 0
Ibrutinib + SNX-5422 Ibrutinib SNX-5422 0 2
SNX-5422 SNX-5422 0 5

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