Drug Detail


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Drug Name Taselisib
Trade Name
Synonyms RG7606|GDC-0032|RG-7604|RO5537381
Drug Descriptions

Taselisib (GDC-0032) is a beta isoform-sparing PI3K inhibitor, with greater activity against oncogenic mutants of PIK3CA (PMID: 23662903, PMID: 31439579).

DrugClasses PIK3CA inhibitor 21 PIK3CD inhibitor 27 PIK3CG inhibitor 10
CAS Registry Number 1282512-48-4
NCIT ID C116876


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD6482 + Taselisib AZD6482 Taselisib 0 0
Docetaxel + Taselisib Docetaxel Taselisib 0 1
Enzalutamide + Taselisib Enzalutamide Taselisib 0 1
Everolimus + Taselisib Everolimus Taselisib 0 0
Fulvestrant + Palbociclib + Taselisib Fulvestrant Palbociclib Taselisib 0 0
Fulvestrant + Taselisib Fulvestrant Taselisib 0 1
Letrozole + Taselisib Letrozole Taselisib 1 0
Neratinib + Taselisib Neratinib Taselisib 0 0
Paclitaxel + Taselisib Paclitaxel Taselisib 0 1
Palbociclib + Taselisib Palbociclib Taselisib 2 0
Radiotherapy + Taselisib Radiotherapy Taselisib 3 0
Tamoxifen + Taselisib Tamoxifen Taselisib 0 0
Taselisib Taselisib 23 5
Taselisib + USP7-797 Taselisib USP7-797 0 0

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