Drug Detail


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Drug Name Rebastinib
Trade Name
Synonyms DCC-2036
Drug Descriptions

Rebastinib (DCC-2036) inhibits BCR-ABL1 and ABL1 mutations including T315I, and has some activity against TIE-2, FLT3, and VEGFR2, potentially resulting in decreased tumor cell growth (PMID: 21481795, PMID: 31763674).

DrugClasses BCR-ABL Inhibitor 26 FLT3 Inhibitor 55 TIE2 Inhibitor 1 VEGFR2 Inhibitor 35


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Rebastinib Carboplatin Rebastinib 1 1
Eribulin + Rebastinib Eribulin Rebastinib 0 1
Paclitaxel + Rebastinib Paclitaxel Rebastinib 1 2
Rebastinib Rebastinib 1 0

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