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Drug Name Tivozanib
Trade Name Fotivda
Synonyms AV-951|AV951|KIL-8951|KRN 951|KRN-951
Drug Descriptions

Fotivda (tivozanib) inhibits VEGFR1-3, which may result in decreased tumor angiogenesis and proliferation and increased cell death (PMID: 23788831, PMID: 31810797, PMID: 32547647). Fotivda(tivozanib) is FDA approved for use in adult patients with relapsed or refractory advanced renal cell carcinoma who have received two or more prior systemic therapies (FDA.gov).

DrugClasses VEGFR Inhibitor (Pan) 32
CAS Registry Number 475108-18-0
NCIT ID C85444

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Therapy Name Drugs Efficacy Evidence Clinical Trials
23814 + Tivozanib 23814 Tivozanib 1 0
Durvalumab + Tivozanib Durvalumab Tivozanib 0 1
Enzalutamide + Tivozanib Enzalutamide Tivozanib 0 1
Fluorouracil + Leucovorin + Oxaliplatin + Tivozanib Fluorouracil Leucovorin Oxaliplatin Tivozanib 1 0
Nivolumab + Tivozanib Nivolumab Tivozanib 1 0
PLX4720 + Tivozanib PLX4720 Tivozanib 1 0
Tivozanib Tivozanib 5 5


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