Drug Detail


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Drug Name Valrubicin
Trade Name Valstar
Synonyms Antibiotic Ad 32|AD-32
Drug Descriptions

Valstar (valrubicin) is an anthracycline that is metabolized into compounds that inhibit topoisomerase II, resulting in inhibition of DNA synthesis and potentially leading to decreased tumor growth (PMID: 19145271, PMID: 20554745). Valstar (valrubicin) is FDA-approved for treatment of BCG-refractory urinary bladder carcinoma in situ (FDA.gov).

DrugClasses Chemotherapy - Anthracycline 13 TOPO2 inhibitor 5
CAS Registry Number 56124-62-0


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Gemcitabine + Interferon gamma + Mitomycin C + Valrubicin Gemcitabine Interferon gamma Mitomycin C Valrubicin 0 0
Valrubicin Valrubicin 0 1

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