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|Synonyms||Antibiotic Ad 32|AD-32|
Valstar (valrubicin) is an anthracycline that is metabolized into compounds that inhibit topoisomerase II, resulting in inhibition of DNA synthesis and potentially leading to decreased tumor growth (PMID: 19145271, PMID: 20554745). Valstar (valrubicin) is FDA-approved for treatment of BCG-refractory urinary bladder carcinoma in situ (FDA.gov).
|DrugClasses||Chemotherapy - Anthracycline 11 TOPO2 inhibitor 4|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Gemcitabine + interferon gamma + Mitomycin C + Valrubicin||Gemcitabine Mitomycin C Valrubicin interferon gamma||0||0|