Drug Detail


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Drug Name Naquotinib
Trade Name
Synonyms ASP8273
Drug Descriptions

Naquotinib (ASP8273) is a third-generation EGFR inhibitor that binds mutant forms of EGFR, including T790M, and also inhibits AXL, thus may lead to growth inhibition in tumor cells (PMID: 29467275, PMID: 31092564).

DrugClasses AXL Inhibitor 30 EGFR Inhibitor 3rd gen 26
CAS Registry Number 1448232-80-1
NCIT ID C115110


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Therapy Name Drugs Efficacy Evidence Clinical Trials
JBJ-04-125-02 + Naquotinib JBJ-04-125-02 Naquotinib 0 0
Naquotinib Naquotinib 0 5

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