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Drug Name MRK-003
Trade Name
Synonyms
Drug Descriptions

MRK-003 is a gamma-secretase inhibitor which inhibits Notch3 signaling and induces apoptosis in cancer cells (PMID: 17804716).

DrugClasses Gamma secretase inhibitor 12

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Therapy Name Drugs Efficacy Evidence Clinical Trials
JQ1 + MRK-003 JQ1 MRK-003 1 0
MRK-003 MRK-003 21 0
MRK-003 + Paclitaxel MRK-003 Paclitaxel 2 0
MRK-003 + Radiotherapy MRK-003 Radiotherapy 1 0
MRK-003 + SCH772984 MRK-003 SCH772984 1 0


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