Drug Detail


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Drug Name Trebananib
Trade Name
Synonyms AMG 386|AMG386
Drug Descriptions

Trebananib (AMG 386) inhibits angiogenesis through binding to the angiopoietins Ang1 and Ang2, thereby preventing interaction with their receptors (PMID: 32154928).

CAS Registry Number 894356-79-7
NCIT ID C91711


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Trebananib Bevacizumab Trebananib 0 2
Pazopanib + Trebananib Pazopanib Trebananib 0 1
Pegylated liposomal-doxorubicin + Trebananib Pegylated liposomal-doxorubicin Trebananib 0 0
Pembrolizumab + Trebananib Pembrolizumab Trebananib 0 1
Sorafenib + Trebananib Sorafenib Trebananib 0 1
Sunitinib + Trebananib Sunitinib Trebananib 0 1
Trastuzumab + Trebananib Trastuzumab Trebananib 0 1
Trebananib Trebananib 0 5

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