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Drug Name Nazartinib
Trade Name
Synonyms EGF816|EGF-816
Drug Descriptions

Nazartinib (EGF816) is a third generation EGFR inhibitor with selectivity towards mutant forms of EGFR, resulting in inhibition of tumor cell growth (PMID: 27433829, PMID: 31954624).

DrugClasses EGFR Inhibitor 3rd gen 20

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Capmatinib + Nazartinib Capmatinib Nazartinib 0 3
Gefitinib + Nazartinib Gefitinib Nazartinib 0 2
LXH 254 + Nazartinib LXH 254 Nazartinib 0 1
Nazartinib Nazartinib 16 1
Nazartinib + Nivolumab Nazartinib Nivolumab 0 1
Nazartinib + Ribociclib Nazartinib Ribociclib 0 1
Nazartinib + Spartalizumab Nazartinib Spartalizumab 0 1
Nazartinib + Trametinib Nazartinib Trametinib 0 1


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