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Drug Name Rasdegafusp alfa
Trade Name
Synonyms CDX-1401|DEC-205/NY-ESO-1 fusion protein vaccine
Drug Descriptions

Rasdegafusp alfa (CDX-1401) is a DEC-205/NY-ESO-1 fusion protein vaccine that consists of a monoclonal antibody directed against the dendritic cell receptor DEC-205 linked to the tumor-associated antigen DEC-205/NY-ESO-1 fusion protein, which may boost the immune system to attack cancer cells expressing DEC-205/NY-ESO-1 fusion protein (PMID: 24739759).

CAS Registry Number 1587257-96-2
NCIT ID C170362


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Guadecitabine + Rasdegafusp alfa Atezolizumab Guadecitabine Rasdegafusp alfa 0 1
Atezolizumab + Rasdegafusp alfa Atezolizumab Rasdegafusp alfa 0 1
Decitabine + Nivolumab + Poly ICLC + Rasdegafusp alfa Decitabine Nivolumab Poly ICLC Rasdegafusp alfa 0 1
Decitabine + Rasdegafusp alfa Decitabine Rasdegafusp alfa 0 1
Rasdegafusp alfa Rasdegafusp alfa 0 4

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