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Drug Name DNIB0600A
Trade Name
Synonyms Lifastuzumab vedotin
Drug Descriptions

DNIB0600A (lifastuzumab vedotin) is an antibody-drug conjugate targeting SLC34A2 and is conjugated to monomethyl auristatin E, which leads to disruption of the microtubule network in SLC34A2-expressing cancer cells, thereby potentially inhibiting cell proliferation (PMID: 29401246).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Carboplatin + DNIB0600A Bevacizumab Carboplatin DNIB0600A 0 1
Carboplatin + DNIB0600A Carboplatin DNIB0600A 0 1
DNIB0600A DNIB0600A 2 1


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