Drug Detail


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Drug Name DNIB0600A
Trade Name
Synonyms Lifastuzumab vedotin|RG-7599
Drug Descriptions

DNIB0600A (Lifastuzumab vedotin) is an antibody-drug conjugate consists of an antibody targeting SLC34A2 and monomethyl auristatin E, which may lead to disruption of the microtubule network in SLC34A2-expressing cancer cells, thereby potentially inhibiting cell proliferation (PMID: 29401246, PMID: 32534811, PMID: 31540980).

CAS Registry Number 1401812-88-1
NCIT ID C116747


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Carboplatin + DNIB0600A Bevacizumab Carboplatin DNIB0600A 0 1
Carboplatin + DNIB0600A Carboplatin DNIB0600A 0 1
DNIB0600A DNIB0600A 0 1

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