Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
Fostamatinib (R788) binds and inhibits Syk kinase thus interfering with mast cell, macrophage, and B-cell activation as well as downstream events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis (NCI Drug Dictionary).
|DrugClasses||SYK Inhibitor 13|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Fostamatinib + Paclitaxel||Fostamatinib Paclitaxel||0||1|
|Fostamatinib + Silmitasertib||Fostamatinib Silmitasertib||1||0|