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Drug Name | SGI-1027 |
Trade Name | |
Synonyms | SGI 1027 |
Drug Descriptions |
SGI-1027 binds and inhibits DNMT1, DNMT3A, and DNMT3B, which leads to decreased DNA methylation and may result the activation of silenced tumor suppressor genes (PMID: 19417133, PMID: 30344731). |
DrugClasses | DNMT inhibitor (Pan) 5 |
CAS Registry Number | 1020149-73-8 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
SGI-1027 | SGI-1027 | 0 | 0 |