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Krestin (polysaccharide-K) is a mushroom-derived immunomodulator that has been demonstrated to reduce immunosuppression and enhance anti-tumor immunity. Krestin has also been shown to reduce proliferation and induce apoptosis in tumor cells (PMID: 22139128).
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|HER-2/neu intracellular domain protein + Pertuzumab + Polysaccharide-K + Trastuzumab||HER-2/neu intracellular domain protein Pertuzumab Polysaccharide-K Trastuzumab||0||1|
|HER-2/neu intracellular domain protein + Polysaccharide-K + Trastuzumab||HER-2/neu intracellular domain protein Polysaccharide-K Trastuzumab||0||0|