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Drug Name rAD-p53
Trade Name
Synonyms Gendicine|Genkaxin
Drug Descriptions

Gendicine (rAD-p53) is a replication-defective adenoviral vector encoding wild-type TP53, which induces tumor cells to produce wild-type Tp53 and potentially induce apoptosis. Gendicine may also stimulate a cytotoxic T-lymphocyte immune response against tumor cells, and activate natural killer cells (PMID: 29338444, PMID: 32013587, PMID: 30618300).

DrugClasses p53 Gene Therapy 4
CAS Registry Number NA
NCIT ID C85485

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Therapy Name Drugs Efficacy Evidence Clinical Trials
rAD-p53 rAD-p53 0 1


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