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Drug Name | L-685458 |
Trade Name | |
Synonyms | L-685,458 |
Drug Descriptions |
L-685458 is a small molecule which selectively binds and inhibits gamma-secretase inhibiting proteolytic cleavage of downstream targets including NOTCH receptor proteins thus blocking pathway activation in cancer (PMID: 10913280). |
DrugClasses | Gamma secretase inhibitor 13 |
CAS Registry Number | 292632-98-5 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
L-685458 | L-685458 | 0 | 0 |