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Drug Name | EPZ004777 |
Trade Name | |
Synonyms | EPZ4777|EPZ-004777|EPZ 004777 |
Drug Descriptions |
EPZ004777 is a small molecule that inhibits DOT1L, which results in decreased histone H3 lysine 79 dimethylation, and potentially leads to decreased tumor cell proliferation (PMID: 21741596, PMID: 27535106, PMID: 31888761). |
DrugClasses | DOT1L Inhibitor 3 |
CAS Registry Number | 1338466-77-5 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
EPZ004777 | EPZ004777 | 0 | 0 |