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Drug Name JIB-04
Trade Name
Synonyms JIB 04|JIB04
Drug Descriptions

JIB-04 is a selective small molecule inhibitor of the histone demethylases KDM4A, KDM4B, KDM4C, KDM4D, KDM4E, KDM5A, and KDM6B, demonstrating specific activity in cancer cells not seen in matched normal controls, and also induced transcriptional changes reducing cellular proliferation and promoting apoptosis of cancer cells (PMID: 23792809, PMID: 32581546).

DrugClasses KDM4 Inhibitor 4
CAS Registry Number 199596-05-9
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
JIB-04 JIB-04 0 0


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