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Drug Name | JIB-04 |
Trade Name | |
Synonyms | JIB 04|JIB04 |
Drug Descriptions |
JIB-04 is a selective small molecule inhibitor of the histone demethylases KDM4A, KDM4B, KDM4C, KDM4D, KDM4E, KDM5A, and KDM6B, demonstrating specific activity in cancer cells not seen in matched normal controls, and also induced transcriptional changes reducing cellular proliferation and promoting apoptosis of cancer cells (PMID: 23792809, PMID: 32581546). |
DrugClasses | KDM4 Inhibitor 4 |
CAS Registry Number | 199596-05-9 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
JIB-04 | JIB-04 | 0 | 0 |