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Drug Name | RO5126766 |
Trade Name | |
Synonyms | VS-6766|CH5126766 |
Drug Descriptions |
RO5126766 (VS-6766) is dual RAF-MEK1/2 inhibitor with effectiveness against both BRAF and RAS mutated cells (PMID: 25422890). |
DrugClasses | MEK inhibitor (Pan) 22 MEK1 Inhibitor 20 MEK2 Inhibitor 18 RAF Inhibitor (Pan) 20 |
CAS Registry Number | 946128-88-7 |
NCIT ID | C80060 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cetuximab + RO5126766 | Cetuximab RO5126766 | 0 | 1 |
Defactinib + RO5126766 | Defactinib RO5126766 | 0 | 4 |
Everolimus + RO5126766 | Everolimus RO5126766 | 0 | 1 |
RO5126766 | RO5126766 | 13 | 4 |
RO5126766 + Sotorasib | RO5126766 Sotorasib | 0 | 1 |
RO5126766 + VS-4718 | RO5126766 VS-4718 | 0 | 0 |