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Drug Name GDC-0575
Trade Name
Synonyms ARRY-575|RG7741
Drug Descriptions

GDC-0575 selectively inhibits CHK1, which potentially results in increased response to chemotherapeutic agents (PMID: 29162833, PMID: 29788155).

DrugClasses CHK1 Inhibitor 15
CAS Registry Number 1196541-47-5
NCIT ID C116845


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cytarabine + Filgrastim + GDC-0575 Cytarabine Filgrastim GDC-0575 0 0
Cytarabine + GDC-0575 Cytarabine GDC-0575 0 0
GDC-0575 GDC-0575 0 1
GDC-0575 + Gemcitabine GDC-0575 Gemcitabine 4 1

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