Drug Detail


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Drug Name CDX-3379
Trade Name
Synonyms CDX3379|MEDI3379|KTN3379
Drug Descriptions

CDX-3379 (KTN3379) is a monoclonal antibody that targets ERBB3 (HER3) and prevents ligand binding and downstream signaling, potentially leads to inhibition of tumor cell growth (PMID: 31308059).

DrugClasses HER3 (ERBB3) Antibody 23
CAS Registry Number 2070921-00-3
NCIT ID C113333


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Therapy Name Drugs Efficacy Evidence Clinical Trials
CDX-3379 CDX-3379 3 2
CDX-3379 + Cetuximab CDX-3379 Cetuximab 0 2
CDX-3379 + Erlotinib CDX-3379 Erlotinib 0 1
CDX-3379 + Trametinib CDX-3379 Trametinib 0 1
CDX-3379 + Trastuzumab CDX-3379 Trastuzumab 0 1
CDX-3379 + Vemurafenib CDX-3379 Vemurafenib 0 2

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