Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
TAE226 is a dual inhibitor of focal adhesion kinase (FAK) and insulin-like growth factor-I receptor, (IGFIR) resulting in decreased signaling pathway activation, decreased tumor cell growth and invasion, and increased cell-cycle arrest (PMID: 17431114, PMID: 31692287).
|DrugClasses||FAK inhibitor 15 IGF-1R Inhibitor 17|
|CAS Registry Number||761437-28-9|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|